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Fabgennix
UCN2 Polyclonal Antibody, Biotin
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Product Details
UCN2-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken wtihin amino acid region 70-115 of human Urocortin 2 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
UCN2 (Urocortin 2) is a Protein Coding gene. Diseases associated with UCN2 include Body Mass Index Quantitative Trait Locus 11. Among its related pathways are Signaling by GPCR and Presynaptic function of Kainate receptors. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and G protein-coupled receptor binding. An important paralog of this gene is UCN3. This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: prepro-urocortin 2; Stresscopin-related peptide; Ucn II; Urocortin II; Urocortin-2; Urocortin-related peptide
Gene Aliases: SRP; UCN-II; UCN2; UCNI; UR; URP
UniProt ID: (Human) Q96RP3
Entrez Gene ID: (Human) 90226
cAMP biosynthetic process
response to stress
adenylate cyclase-activating G-protein coupled receptor signaling pathway
digestion
cell proliferation
negative regulation of gene expression
cellular response to nutrient levels
negative regulation of luteinizing hormone secretion
response to immobilization stress
negative regulation of follicle-stimulating hormone secretion
cellular response to glucocorticoid stimulus
cellular response to hypoxia
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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