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Invitrogen
UCP1/UCP3 Recombinant Rabbit Monoclonal Antibody (0S10O10)
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Product Details
MA5-37913
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
0S10O10
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of mouse UCP1+UCP3 (P12242)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897833
Product Specific Information
Positive Samples: Mouse skeletal muscle, Mouse fat
Immunogen sequence: MVNPTTSEVQ PTMGVKIFSA GVSACLADII TFPLDTAKVR LQIQGEGQAS STIRYKGVLG TITTLAKTEG LPKLYSGLPA GIQRQISFAS LRIGLYDSVQ EYFSSGRETP ASLGNKISAG LMTGGVAVFI GQPTEVVKVR MQAQSHLHGI KPRYTGTYNA YRVIATTESL STLWKGTTPN LMRNVIINCT ELVTYDLMKG ALVNNKILAD DVPCHLLSAL VAGFCTTLLA SPVDVVKTRF INSLPGQYPS VPSCAMSMYT KEGPTAFFKG FVASFLRLGS WNVIMFVCFE QLKKELMKSR QTVDCTT
Target Information
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mitochondrial brown fat uncoupling protein 1; mitochondrial uncoupling protein 3; Putative mitochondrial transporter UCP3; Solute carrier family 25 member 7; Solute carrier family 25 member 9; Thermogenin; UCP 1; UCP 3; uncoupling protein 1, mitochondrial; Uncoupling protein 3; Uncoupling protein 3, mitochondrial; uncoupling protein, mitochondrial; Uncoupling protein-3
Gene Aliases: AI385626; AI645527; Slc25a7; Slc25a9; Ucp; UCP-3; Ucp1; Ucp3; Ucpa; Uncp
UniProt ID: (Rat) P04633, (Mouse) P12242, (Mouse) P56501, (Rat) P56499
Entrez Gene ID: (Rat) 24860, (Mouse) 22227, (Mouse) 22229, (Rat) 25708
response to superoxide
response to hypoxia
fatty acid metabolic process
transport
mitochondrial transport
proton transport
transmembrane transport
generation of precursor metabolites and energy
regulation of transcription from RNA polymerase II promoter
cellular response to hormone stimulus
positive regulation of multicellular organismal metabolic process
response to steroid hormone
aging
response to nutrient
response to cold
response to activity
response to insulin
response to glucocorticoid
hydrogen ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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