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Invitrogen
UGT2B4 Polyclonal Antibody
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UGT2B4 Antibody (PA5-92155) in WB
Western blot analysis of UGT2B4 in extracts of various cell lines. Samples were incubated with UGT2B4 Polyclonal antibody (Product # PA5-92155) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-92155
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human UGT2B4 (NP_0669622)
Conjugate
Form
Liquid
Concentration
1.84 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806395
Product Specific Information
Immunogen sequence: LHCKPAKPLP KEMEEFVQSS GENGVVVFSL GSMVSNTSEE RANVIASALA KIPQKVLWRF DGNKPDTLGL NTRLYKWIPQ NDLLGHPKTR AFITHGGANG IYEAIYHGIP MVGVPLFADQ PDNIAHMKAK GAAVSLDFHT MSSTDLLNAL KTVINDPLYK ENAMKLSRIH HDQPVKPLDR AVFWIEFVMR HKGAKHLRVA A; Positive Samples: 22Rv1, B cells, HT-1080, Mouse liver, Mouse brain, Mouse kidney, Rat kidney; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein
Target Information
UGT2B4 belongs to the UDP-glycosyltransferase family. UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HLUG25; hyodeoxycholic acid; Hyodeoxycholic acid-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B4; UDP-glucuronosyltransferase 2B4; UDP-glucuronyltransferase, family 2, beta-4; UDPGT 2B4; UDPGTh-1
Gene Aliases: HLUG25; UDPGT2B4; UDPGTh-1; UDPGTH1; UGT2B11; UGT2B4
UniProt ID: (Human) P06133
Entrez Gene ID: (Human) 7363
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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