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Proteintech
UNC119 Polyclonal Antibody
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Product Details
13065-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UNC119 Fusion Protein Ag3757 (1-240 aa encoded by BC027176)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKVKKGGGG AGTATESAPG PSGQSVAPIP QPPAESESGS ESEPDAGPGP RPGPLQRKQP IGPEDVLGLQ RITGDYLCSP EENIYKIDFV RFKIRDMDSG TVLFEIKKPP VSERLPINRR DLDPNAGRFV RYQFTPAFLR LRQVGATVEF TVGDKPVNNF RMIERHYFRN QLLKSFDFHF GFCIPSSKNT CEHIYDFPPL SEELISEMIR HPYETQSDSF YFVDDRLVMH NKADYSYSGT P (1-240 aa encoded by BC027176)
Target Information
This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hRG4; mRG4; POC7 centriolar protein homolog A; Protein unc-119 homolog A; retinal gene 4; Retinal protein 4; rRG4; unc-119 homolog
Gene Aliases: D11Bhm52; HRG4; IMD13; MRG4; POC7; POC7A; RG4; RRG4; Rtg4; UNC119; Unc119h; Uncl19
UniProt ID: (Human) Q13432, (Mouse) Q9Z2R6, (Rat) Q62885
Entrez Gene ID: (Dog) 491169, (Human) 9094, (Mouse) 22248, (Rat) 29402
transport
endocytosis
visual perception
protein transport
lipoprotein transport
response to stimulus
positive regulation of protein tyrosine kinase activity
negative regulation of clathrin-mediated endocytosis
negative regulation of caveolin-mediated endocytosis
chemical synaptic transmission
phototransduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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