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Immunogen sequence: IKVYNTSGAV TPQDDLSEFT SKLSPQMTQS LLENEALSLK NQSLARQTDP SCTAFGSFNS LGGHLIVPNS GVSLLIPAGA IPQGRVYEMY VTVHRKETMR
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin -like domains and 2 type I thrombospondin motifs in the extracellular region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Netrin receptor UNC5C; Protein unc-5 homolog 3; Protein unc-5 homolog C; unc-5 homolog 3; unc-5 homolog C; unc5 (C.elegans homolog) c
Gene Aliases: UNC5C; UNC5H3
UniProt ID: (Human) O95185
Entrez Gene ID: (Human) 8633
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