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Invitrogen
UNK Polyclonal Antibody
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Product Details
PA5-55737
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human UNK. Recombinant protein control fragment (Product #RP-93268).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649281
Product Specific Information
Immunogen sequence: IYKSTKCNDM QQSGSCPRGP FCAFAHVEQP PLSDDLQPSS AVSSPTQPGP VLYMPSAAGD SVPVSPSSPH APDLSALLCR NSSLGSPSNL CGSPPGSIRK PPNLEGIVFP GES
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 86%.
Target Information
Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RING finger protein unkempt homolog; unkempt homolog; Zinc finger CCCH domain-containing protein 5; zinc finger CCCH type domain containing 5; zinc finger CCCH-type containing 5; zinc finger CCCH-type domain containing 5
Gene Aliases: KIAA1753; UNK; UNKEMPT; ZC3H5; ZC3HDC5
UniProt ID: (Human) Q9C0B0
Entrez Gene ID: (Human) 85451
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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