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FIGURE: 1 / 1
UPP1 Antibody (PA5-88945) in WB
Western blot analysis of UPP1 in extracts of various cell lines. Samples were incubated with UPP1 Polyclonal antibody (Product # PA5-88945) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
PA5-88945
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 89-173 of human UPP1 (NP_0012743571)
Conjugate
Form
Liquid
Concentration
1.59 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805242
Product Specific Information
Immunogen sequence: SYTEKDKQAY LEAAYAAGVR NIEMESSVFA AMCSACGLQA AVVCVTLLNR LEGDQISSPR NVLSEYQQRP QRLVSYFIKK KLSKA; Positive Samples: HT-29, A431, A549, 293T, HeLa
Target Information
UPP1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:7488099). The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: UPase 1; urdPase 1; Uridine phosphorylase 1
Gene Aliases: UDRPASE; UP; UPASE; UPP; UPP1
UniProt ID: (Human) Q16831
Entrez Gene ID: (Human) 7378
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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