Proteintech

UQCRB Polyclonal Antibody

UQCRB Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 8

UQCRB Antibody (10756-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using (Product # 10756-1-AP) (UQCRB antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

UQCRB Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

10756-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 13 publications 13 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

UQCRB Fusion Protein Ag1127 (1-111 aa encoded by BC005230)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAGKQAVSA SGKWLDGIRK WYYNAAGFNK LGLMRDDTIY EDEDVKEAIR RLPENLYNDR MFRIKRALDL NLKHQILPKE QWTKYEEENF YLEPYLKEVI RERKEREEWA KK (1-111 aa encoded by BC005230)

Target Information

UQCRB encodes a product that is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This component is involved in redox-linked proton pumping.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Novel prognostic features and personalized treatment strategies for mitochondria-related genes in glioma patients.

Frontiers in endocrinology

Wu J,Zhou J,Chai Y,Qin C,Cai Y,Xu D,Lei Y,Mei Z,Li M,Shen L,Fang G,Yang Z,Cai S,Xiong N

Tue Apr 25 00:00:00 UTC 2023

Novel prognostic features and personalized treatment strategies for mitochondria-related genes in glioma patients.

Frontiers in endocrinology

Wu J,Zhou J,Chai Y,Qin C,Cai Y,Xu D,Lei Y,Mei Z,Li M,Shen L,Fang G,Yang Z,Cai S,Xiong N

Tue Apr 25 00:00:00 UTC 2023

Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3.

Free radical biology & medicine

Zhang Q,Ren J,Wang F,Pan M,Cui L,Li M,Qu F

Fri Jul 01 00:00:00 UTC 2022

Effect of downregulated citrate synthase on oxidative phosphorylation signaling pathway in HEI-OC1 cells.

Proteome science

Xu X,Liu Y,Luan J,Liu R,Wang Y,Liu Y,Xu A,Zhou B,Han F,Shang W

Wed Sep 07 00:00:00 UTC 2022

Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly.

Nature chemical biology

Bennett CF,O'Malley KE,Perry EA,Balsa E,Latorre-Muro P,Riley CL,Luo C,Jedrychowski M,Gygi SP,Puigserver P

Tue Jun 01 00:00:00 UTC 2021

Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance.

Science advances

Ma W,Gil HJ,Liu X,Diebold LP,Morgan MA,Oxendine-Burns MJ,Gao P,Chandel NS,Oliver G

Thu Apr 01 00:00:00 UTC 2021

Tetracyclines promote survival and fitness in mitochondrial disease models.

Nature metabolism

Perry EA,Bennett CF,Luo C,Balsa E,Jedrychowski M,O'Malley KE,Latorre-Muro P,Ladley RP,Reda K,Wright PM,Gygi SP,Myers AG,Puigserver P

Fri Jan 01 00:00:00 UTC 2021

Hepatic HuR modulates lipid homeostasis in response to high-fat diet.

Nature communications

Zhang Z,Zong C,Jiang M,Hu H,Cheng X,Ni J,Yi X,Jiang B,Tian F,Chang MW,Su W,Zhu L,Li J,Xiang X,Miao C,Gorospe M,de Cabo R,Dou Y,Ju Z,Yang J,Jiang C,Yang Z,Wang W

Tue Jun 16 00:00:00 UTC 2020

TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III.

Molecular cell

Bottani E,Cerutti R,Harbour ME,Ravaglia S,Dogan SA,Giordano C,Fearnley IM,D'Amati G,Viscomi C,Fernandez-Vizarra E,Zeviani M

Thu Jul 06 00:00:00 UTC 2017

TTC19 Plays a Husbandry Role on UQCRFS1 Turnover in the Biogenesis of Mitochondrial Respiratory Complex III.

Molecular cell

Bottani E,Cerutti R,Harbour ME,Ravaglia S,Dogan SA,Giordano C,Fearnley IM,D'Amati G,Viscomi C,Fernandez-Vizarra E,Zeviani M

Thu Jul 06 00:00:00 UTC 2017

Fatal familial insomnia: mitochondrial and protein synthesis machinery decline in the mediodorsal thalamus.

Brain pathology (Zurich, Switzerland)

Frau-Méndez MA,Fernández-Vega I,Ansoleaga B,Blanco Tech R,Carmona Tech M,Antonio Del Rio J,Zerr I,Llorens F,José Zarranz J,Ferrer I

Sun Jan 01 00:00:00 UTC 2017

CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.

Disease markers

Han Y,Sun S,Zhao M,Zhang Z,Gong S,Gao P,Liu J,Zhou J,Ma D,Gao Q,Wu P

Mon Feb 20 00:00:00 UTC 2017

CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.

Disease markers

Han Y,Sun S,Zhao M,Zhang Z,Gong S,Gao P,Liu J,Zhou J,Ma D,Gao Q,Wu P

Mon Feb 20 00:00:00 UTC 2017

Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt-Jakob Disease.

Journal of neuropathology and experimental neurology

Ansoleaga B,Garcia-Esparcia P,Llorens F,Hernández-Ortega K,Carmona Tech M,Antonio Del Rio J,Zerr I,Ferrer I

Mon Aug 01 00:00:00 UTC 2016

Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt-Jakob Disease.

Journal of neuropathology and experimental neurology

Ansoleaga B,Garcia-Esparcia P,Llorens F,Hernández-Ortega K,Carmona Tech M,Antonio Del Rio J,Zerr I,Ferrer I

Mon Aug 01 00:00:00 UTC 2016

Quantitative proteomics reveals oxygen-dependent changes in neuronal mitochondria affecting function and sensitivity to rotenone.

Journal of proteome research

Villeneuve L,Tiede LM,Morsey B,Fox HS

Fri Oct 04 00:00:00 UTC 2013

Quantitative proteomics reveals oxygen-dependent changes in neuronal mitochondria affecting function and sensitivity to rotenone.

Journal of proteome research

Villeneuve L,Tiede LM,Morsey B,Fox HS

Fri Oct 04 00:00:00 UTC 2013

Mitochondrial complex III ROS regulate adipocyte differentiation.

Cell metabolism

Tormos KV,Anso E,Hamanaka RB,Eisenbart J,Joseph J,Kalyanaraman B,Chandel NS

Wed Oct 05 00:00:00 UTC 2011

Mitochondrial complex III ROS regulate adipocyte differentiation.

Cell metabolism

Tormos KV,Anso E,Hamanaka RB,Eisenbart J,Joseph J,Kalyanaraman B,Chandel NS

Wed Oct 05 00:00:00 UTC 2011

Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain.

Neurobiology of aging

Li N,Bates DJ,An J,Terry DA,Wang E

Sun May 01 00:00:00 UTC 2011

Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain.

Neurobiology of aging

Li N,Bates DJ,An J,Terry DA,Wang E

Sun May 01 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: Complex III subunit 7; Complex III subunit VII; Cytochrome b-c1 complex subunit 7; mitochondrial ubiquinone-binding protein; QP-C; ubiquinol-cytochrome c reductase binding protein-like; Ubiquinol-cytochrome c reductase complex 14 kDa protein; ubiquinol-cytochrome c reductase, complex III subunit VI

View more View less

Gene Aliases: 2210415M14Rik; MC3DN3; QCR7; QP-C; QPC; UQBC; UQBP; UQCR6; UQCRB; Uqcrbl; UQPC

View more View less

UniProt ID: (Human) P14927

View more View less

Entrez Gene ID: (Human) 7381, (Mouse) 67530, (Rat) 362897

View more View less

Function(s)

protein binding ubiquinol-cytochrome-c reductase activity protein complex binding

Process(es)

mitochondrial electron transport, ubiquinol to cytochrome c transport oxidation-reduction process protein heterooligomerization oxidative phosphorylation aerobic respiration mitochondrial respiratory chain complex III assembly hydrogen ion transmembrane transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

UQCRB Polyclonal Antibody

UQCRB Antibody (10756-1-AP) in IHC (P)

Product Details

10756-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!