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Immunogen sequence: MKVLLLKDA KEDDCGQDPY IRELGLYGLE ATLIPVLSFE FLSLPSFSEK LSHPEDYGGL IFTSPRAVEA AELCLEQNNK TEVWERSLKE KWNAKSVYVV GNATASLVSK IGLDTEGETC GNAEKLAEYI CSRESSALPL LFPCGNLKRE ILPKALKDKG IAMESITVYQ TVAHPGIQGN LNSYYSQQGV PASITFFSPS GLTYSLKHIQ ELSGDNIDQI KFAAIGPTTA RALAAQGLPV SCTAESPTPQ ALATGIRKAL QPHGCC (1-265 aa encoded by B C002573)
The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hydroxymethylbilane hydrolyase; Hydroxymethylbilane hydrolyase [cyclizing]; urogen III synthase; UROIIIS; uroporphyrinogen III co-synthase; Uroporphyrinogen-III cosynthase; Uroporphyrinogen-III synthase
Gene Aliases: AI415298; UROIIIS; UROS; Uros3
UniProt ID: (Human) P10746, (Mouse) P51163
Entrez Gene ID: (Human) 7390, (Rat) 309070, (Mouse) 22276
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