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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • USP10 Antibodies

          Proteintech

          USP10 Polyclonal Antibody

          11 References
          View all (29) USP10 antibodies

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          Cite USP10 Polyclonal Antibody

          • Antibody Testing Data (7)
          USP10 Antibody in Immunocytochemistry (ICC/IF)
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          USP10 Antibody in Immunocytochemistry (ICC/IF)
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          FIGURE: 1 / 7

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          USP10 Antibody (19374-1-AP) in ICC/IF

          Immunofluorescent analysis of Hela cells, using USP10 antibody 19374-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          USP10 Antibody in Immunocytochemistry (ICC/IF)
          USP10 Antibody in Western Blot (WB)
          USP10 Antibody in Western Blot (WB)
          USP10 Antibody in Western Blot (WB)
          USP10 Antibody in Western Blot (WB)
          USP10 Antibody in Western Blot (WB)
          USP10 Antibody in Immunoprecipitation (IP)

          Product Details

          19374-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 5 publications 5 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          View 3 publications 3 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          USP10 Fusion Protein Ag7233 (444-798 aa encoded by BC000263)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.19 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: KFIPLYSKV QRPCTSTPMI DSFVRLMNEF TNMPVPPKPR QALGDKIVRD IRPGAAFEPT YIYRLLTVNK SSLSEKGRQE DAEEYLGFIL NGLHEEMLNL KKLLSPSNEK LTISNGPKNH SVNEEEQEEQ GEGSEDEWEQ VGPRNKTSVT RQADFVQTPI TGIFGGHIRS VVYQQSSKES ATLQPFFTLQ LDIQSDKIRT VQDALESLVA RESVQGYTTK TKQEVEISRR VTLEKLPPVL VLHLKRFVYE KTGGCQKLIK NIEYPVDLEI SKELLSPGVK NKNFKCHRTY RLFAVVYHHG NSATGGHYTT DVFQIGLNGW LRIDDQTVKV INQYQVVKPT AERTAYLLYY RRVDLL (444-798 aa encoded by BC000263)

          Target Information

          USP10, also known as ubiquitin specific peptidase 10, belongs to the ubiquitin-specific protease family of cysteine proteases. USP10 functions to catalyze the cleavage of ubiquitin from ubiquitin-conjugated protein substrates such as p53/TP53, SNX3 and CFTR. USP10 has been identified as a subunit of DNA-bound androgen receptor (AR) complexes and may play a role in the activity of the DNA-bound androgen receptor complex. USP10 also acts as an essential regulator of p53/TP53 stability and is thought to function as a tumor suppressor.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Deubiquitinating enzyme 10; MGC2621; ubiquintin c-terminal hydrolase related polypeptide; Ubiquitin carboxyl-terminal hydrolase 10; ubiquitin specific protease 10; Ubiquitin thioesterase 10; ubiquitin thiolesterase 10; Ubiquitin-specific-processing protease 10

          View more View less

          Gene Aliases: 2610014N07Rik; KIAA0190; mKIAA0190; Ode-1; UBPO; Uchrp; USP10

          View more View less

          UniProt ID: (Human) Q14694, (Mouse) P52479, (Rat) Q3KR59

          View more View less

          Entrez Gene ID: (Human) 9100, (Mouse) 22224, (Rat) 307905

          View more View less

          Function(s)
          p53 binding cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity protein binding ion channel binding poly(A) RNA binding peptidase activity cysteine-type peptidase activity hydrolase activity thiol-dependent ubiquitinyl hydrolase activity
          Process(es)
          DNA repair proteolysis ubiquitin-dependent protein catabolic process autophagy cellular response to DNA damage stimulus regulation of autophagy protein deubiquitination DNA damage response, signal transduction by p53 class mediator proteasome-mediated ubiquitin-dependent protein catabolic process regulation of proteasomal protein catabolic process translesion synthesis negative regulation of I-kappaB kinase/NF-kappaB signaling cellular response to interleukin-1
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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