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USP11 Antibody (MA5-37644) in WB
Western Blot analysis of USP11 using the USP11 Monoclonal Antibody (Product # MA5-37644) at a dilution of 1:1,000 in Jurkat, Hela, LNCaP cells (from left to right) (35 µg per lane). A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody.
Product Details
MA5-37644
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1220CT620.193.189
Immunogen
KLH conjugated synthetic peptide between 32-300 amino acids from the N-terminal region of human USP11
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897570
Target Information
USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the Ub pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and with the tumor suppressor BRCA2. Through these associations, USP11 functions to either inhibit ubiquitination of these proteins or to remove ubiquitin residues that have already been attached to these proteins. USP11 is implicated in several X-linked retinal diseases and, due to its ability to deubiquitinate BRCA2, may play a role in tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: deubiquitinating enzyme 11; RP4-659F15.2; ubiquitin carboxyl-terminal hydrolase, X-linked; ubiquitin thioesterase 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin-specific-processing protease 11
Gene Aliases: UHX1
Entrez Gene ID: (Human) 8237
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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