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Invitrogen
USP2 Polyclonal Antibody
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Product Details
PA5-33099
Product Specifications
Species Reactivity
Bovine,
Dog,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 17 amino acid peptide from C-terminus of human USP2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550558
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Elephant, Panda, Horse, Rabbit, Opossum (100%); Pig (94%).
Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.
Target Information
Ubiquitin is a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 41 kDa ubiquitin-specific protease; Deubiquitinating enzyme 2; Ubiquitin carboxyl-terminal hydrolase 2; ubiquitin specific peptidase 2; ubiquitin specific protease 12; ubiquitin specific protease 2; ubiquitin specific protease 9; Ubiquitin thioesterase 2; ubiquitin thiolesterase 2; Ubiquitin-specific-processing protease 2; Ubiquitin-specific-processing protease testis; UBP-t
Gene Aliases: B930035K21Rik; BOS_14469; I79_023597; MNCb-0190; UBP-t; UBP41; Ubp69; USP2; USP9
UniProt ID: (Human) O75604, (Bovine) Q2KHV7, (Mouse) O88623, (Rat) Q5U349
Entrez Gene ID: (Rabbit) 100339033, (Human) 9099, (Dog) 608188, (Bovine) 522980, (Mouse) 53376, (Chinese hamster) 100758523, (Rat) 115771
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
cyclin binding
ubiquitin protein ligase binding
identical protein binding
metal ion binding
obsolete ubiquitin thiolesterase activity
cysteine-type peptidase activity
peptidase activity
hydrolase activity
thiol-dependent ubiquitinyl hydrolase activity
negative regulation of transcription from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
cell cycle
muscle organ development
protein deubiquitination
circadian regulation of gene expression
entrainment of circadian clock by photoperiod
locomotor rhythm
positive regulation of mitotic cell cycle
circadian behavior
negative regulation of skeletal muscle tissue development
positive regulation of skeletal muscle tissue development
protein stabilization
regulation of transcription, DNA-templated
proteolysis
proteasome-mediated ubiquitin-dependent protein catabolic process
rhythmic process
regulation of proteasomal protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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