Proteintech

USP24 Polyclonal Antibody

USP24 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 9

USP24 Antibody (13126-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using 13126-1-AP (USP24 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

USP24 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

13126-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 10 publications 10 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400

Immunocytochemistry (ICC/IF)

1:10-1:100

View 2 publications 2 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

USP24 Fusion Protein Ag3779 (2312-2620 aa encoded by BC029660)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MISFLLGAS RQNNQIRRWS SAQAREFGNL HNTVALLVLH SDVSSQRNVA PGIFKQRPPI SIAPSSPLLP LHEEVEALLF MSEGKPYLLE VMFALRELTG SLLALIEMVV YCCFCNEHFS FTMLHFIKNQ LETAPPHELK NTFQLLHEIL VIEDPIQVER VKFVFETENG LLALMHHSNH VDSSRCYQCV KFLVTLAQKC PAAKEYFKEN SHHWSWAVQW LQKKMSEHYW TPQSNVSNET STGKTFQRTI SAQDTLAYAT ALLNEKEQSG SSNGSESSPA NENGDRHLQQ GSESPMMIGE LRSDLDDVDP (2312-2620 aa encoded by BC029660)

Target Information

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.

Virologica Sinica

Zang L,Gu J,Yang X,Yuan Y,Guo H,Zhou W,Ma J,Chen Y,Wu Y,Zheng H,Shi W

Wed Feb 01 00:00:00 UTC 2023

LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer.

Molecular cancer

Sun Z,Zhang R,Zhang X,Sun Y,Liu P,Francoeur N,Han L,Lam WY,Yi Z,Sebra R,Walsh M,Yu J,Zhang W

Sat Jul 16 00:00:00 UTC 2022

USP24 promotes drug resistance during cancer therapy.

Cell death and differentiation

Wang SA,Young MJ,Wang YC,Chen SH,Liu CY,Lo YA,Jen HH,Hsu KC,Hung JJ

Wed Sep 01 00:00:00 UTC 2021

USP24 promotes drug resistance during cancer therapy.

Cell death and differentiation

Wang SA,Young MJ,Wang YC,Chen SH,Liu CY,Lo YA,Jen HH,Hsu KC,Hung JJ

Wed Sep 01 00:00:00 UTC 2021

USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway.

International journal of biological sciences

He H,Yi L,Zhang B,Yan B,Xiao M,Ren J,Zi D,Zhu L,Zhong Z,Zhao X,Jin X,Xiong W

Wed Mar 16 00:00:00 UTC 2022

USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway.

International journal of biological sciences

He H,Yi L,Zhang B,Yan B,Xiao M,Ren J,Zi D,Zhu L,Zhong Z,Zhao X,Jin X,Xiong W

Wed Mar 16 00:00:00 UTC 2022

A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.

Nature communications

Kim JM,Yang YS,Park KH,Ge X,Xu R,Li N,Song M,Chun H,Bok S,Charles JF,Filhol-Cochet O,Boldyreff B,Dinter T,Yu PB,Kon N,Gu W,Takarada T,Greenblatt MB,Shim JH

Fri May 08 00:00:00 UTC 2020

USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy.

Scientific reports

Wang SA,Young MJ,Jeng WY,Liu CY,Hung JJ

Mon Nov 30 00:00:00 UTC 2020

USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy.

Scientific reports

Wang SA,Young MJ,Jeng WY,Liu CY,Hung JJ

Mon Nov 30 00:00:00 UTC 2020

The PARK10 gene USP24 is a negative regulator of autophagy and ULK1 protein stability.

Autophagy

Thayer JA,Awad O,Hegdekar N,Sarkar C,Tesfay H,Burt C,Zeng X,Feldman RA,Lipinski MM

Wed Jan 01 00:00:00 UTC 2020

The PARK10 gene USP24 is a negative regulator of autophagy and ULK1 protein stability.

Autophagy

Thayer JA,Awad O,Hegdekar N,Sarkar C,Tesfay H,Burt C,Zeng X,Feldman RA,Lipinski MM

Wed Jan 01 00:00:00 UTC 2020

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.

Nature communications

Bufalieri F,Infante P,Bernardi F,Caimano M,Romania P,Moretti M,Lospinoso Severini L,Talbot J,Melaiu O,Tanori M,Di Magno L,Bellavia D,Capalbo C,Puget S,De Smaele E,Canettieri G,Guardavaccaro D,Busino L,Peschiaroli A,Pazzaglia S,Giannini G,Melino G,Locatelli F,Gulino A,Ayrault O,Fruci D,Di Marcotullio L

Wed Jul 24 00:00:00 UTC 2019

Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.

Journal of virology

Sun Y,Bao Q,Xuan B,Xu W,Pan D,Li Q,Qian Z

Sun Jul 01 00:00:00 UTC 2018

Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-Specific Protease 24 and Regulating Iron Metabolism.

Journal of virology

Sun Y,Bao Q,Xuan B,Xu W,Pan D,Li Q,Qian Z

Sun Jul 01 00:00:00 UTC 2018

USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy.

Nature communications