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Product Details
PA5-30457
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human USP33. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2547931
Product Specific Information
Recommended positive controls: HeLa, HepG2.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (83%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
DNA-directed RNA polymerase I subunit RPA43 or Twist neighbor protein (Twistnb)belongs to the eukaryotic RPA43 RNA polymerase subunit family. It catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.Twistnb is the component of RNA polymerase I which synthesizes ribosomal RNA precursors. It is widely expressed in all fetal and adult tissues, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. Twist genes are essential for embryonic development and are conserved from jellyfish to human.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Deubiquitinating enzyme 33; hVDU1; pVHL-interacting deubiquitinating enzyme 1; Ubiquitin carboxyl-terminal hydrolase 33; Ubiquitin thioesterase 33; ubiquitin thiolesterase 33; Ubiquitin-specific-processing protease 33; VHL-interacting deubiquitinating enzyme 1
Gene Aliases: KIAA1097; USP33; VDU1
UniProt ID: (Human) Q8TEY7
Entrez Gene ID: (Human) 23032
ubiquitin-dependent protein catabolic process
endocytosis
axon guidance
regulation of G-protein coupled receptor protein signaling pathway
cellular response to starvation
regulation of autophagy
cell migration
protein deubiquitination
negative regulation of protein binding
positive regulation of protein binding
protein stabilization
centrosome duplication
protein K63-linked deubiquitination
protein K48-linked deubiquitination
Performance Guarantee
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