Proteintech

USP36 Polyclonal Antibody

FIGURE: 1 / 6

USP36 Antibody (14783-1-AP) in WB

Jurkat cells were subjected to SDS PAGE followed by western blot with 14783-1-AP (USP36 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

USP36 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

14783-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 12 publications 12 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

View 6 publications 6 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

USP36 Fusion Protein Ag6411 (1-285 aa encoded by BC038983)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MPIVDKLKE ALKPGRKDSA DDGELGKLLA SSAKKVLLQK IEFEPASKSF SYQLEALKSK YVLLNPKTEG ASRHKSGDDP PARRQGSEHT YESCGDGVPA PQKVLFPTER LSLRWERVFR VGAGLHNLGN TCFLNATIQC LTYTPPLANY LLSKEHARSC HQGSFCMLCV MQNHIVQAFA NSGNAIKPVS FIRDLKKIAR HFRFGNQEDA HEFLRYTIDA MQKACLNGCA KCVLPHPPSQ GFGHLFYMVA AEHSYGNSQP GTFLPRLPLG RRGRICLWVL KLLEPK (1-285 aa encoded by B C038983)

Target Information

May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.

Oncogene

Zheng M,Ai Z,Guo Y,Chen Y,Xie P,An W

Sun Jan 01 00:00:00 UTC 2023

Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.

Oncogene

Zheng M,Ai Z,Guo Y,Chen Y,Xie P,An W

Sun Jan 01 00:00:00 UTC 2023

Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.

Oncogene

Zheng M,Ai Z,Guo Y,Chen Y,Xie P,An W

Sun Jan 01 00:00:00 UTC 2023

The Ubiquitin-specific Protease USP36 Associates with the Microprocessor Complex and Regulates miRNA Biogenesis by SUMOylating DGCR8.

Cancer research communications

Li Y,Carey TS,Feng CH,Zhu HM,Sun XX,Dai MS

Wed Mar 01 00:00:00 UTC 2023

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

Nucleic acids research

Chen Y,Li Y,Dai RS,Savage JC,Shinde U,Klimek J,David LL,Young EA,Hafner M,Sears RC,Sun XX,Dai MS

Mon May 08 00:00:00 UTC 2023

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

Nucleic acids research

Chen Y,Li Y,Dai RS,Savage JC,Shinde U,Klimek J,David LL,Young EA,Hafner M,Sears RC,Sun XX,Dai MS

Mon May 08 00:00:00 UTC 2023

Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc.

Cell death and differentiation

Peng Y,Liu J,Wang Z,Cui C,Zhang T,Zhang S,Gao P,Hou Z,Liu H,Guo J,Zhang J,Wen Y,Wei W,Zhang L,Liu J,Long J

Thu Sep 01 00:00:00 UTC 2022

Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules.

Nature communications

Wang T,Tian X,Kim HB,Jang Y,Huang Z,Na CH,Wang J

Fri Sep 23 00:00:00 UTC 2022

USP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP.

Cell death & disease

Zhang W,Luo J,Xiao Z,Zang Y,Li X,Zhou Y,Zhou J,Tian Z,Zhu J,Zhao X

Mon Dec 05 00:00:00 UTC 2022

USP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP.

Cell death & disease

Zhang W,Luo J,Xiao Z,Zang Y,Li X,Zhou Y,Zhou J,Tian Z,Zhu J,Zhao X

Mon Dec 05 00:00:00 UTC 2022

USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway.

Frontiers in cell and developmental biology

Zhu S,Hou S,Lu Y,Sheng W,Cui Z,Dong T,Feng H,Wan Q

Thu May 13 00:00:00 UTC 2021

USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway.

Frontiers in cell and developmental biology

Zhu S,Hou S,Lu Y,Sheng W,Cui Z,Dong T,Feng H,Wan Q

Thu May 13 00:00:00 UTC 2021

USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway.

Frontiers in cell and developmental biology

Zhu S,Hou S,Lu Y,Sheng W,Cui Z,Dong T,Feng H,Wan Q

Thu May 13 00:00:00 UTC 2021

Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity.

International journal of molecular sciences

Pariano M,Pieroni S,De Luca A,Iannitti RG,Borghi M,Puccetti M,Giovagnoli S,Renga G,D'Onofrio F,Bellet MM,Stincardini C,Della-Fazia MA,Servillo G,van de Veerdonk FL,Costantini C,Romani L

Fri Jun 18 00:00:00 UTC 2021

The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.

Nucleic acids research

Yan Y,Xu Z,Huang J,Guo G,Gao M,Kim W,Zeng X,Kloeber JA,Zhu Q,Zhao F,Luo K,Lou Z

Wed Dec 16 00:00:00 UTC 2020

The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.

Nucleic acids research

Yan Y,Xu Z,Huang J,Guo G,Gao M,Kim W,Zeng X,Kloeber JA,Zhu Q,Zhao F,Luo K,Lou Z

Wed Dec 16 00:00:00 UTC 2020

The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.

Nucleic acids research

Yan Y,Xu Z,Huang J,Guo G,Gao M,Kim W,Zeng X,Kloeber JA,Zhu Q,Zhao F,Luo K,Lou Z

Wed Dec 16 00:00:00 UTC 2020

USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.

Biochemical and biophysical research communications

Liu Q,Sheng W,Ma Y,Zhen J,Roy S,Alvira Jafar C,Xin W,Wan Q

Tue May 28 00:00:00 UTC 2019

USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.

Biochemical and biophysical research communications

Liu Q,Sheng W,Ma Y,Zhen J,Roy S,Alvira Jafar C,Xin W,Wan Q

Tue May 28 00:00:00 UTC 2019

USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.

Biochemical and biophysical research communications

Liu Q,Sheng W,Ma Y,Zhen J,Roy S,Alvira Jafar C,Xin W,Wan Q

Tue May 28 00:00:00 UTC 2019

PME-1 is regulated by USP36 in ERK and Akt signaling pathways.

FEBS letters