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          • Primary Antibodies ›
          • USP36 Antibodies

          Invitrogen

          USP36 Polyclonal Antibody

          View all (20) USP36 antibodies
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          Cite USP36 Polyclonal Antibody

          • Antibody Testing Data (1)
          USP36 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          USP36 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          USP36 Antibody (PA5-88995) in WB

          Western blot analysis of USP36 in extracts of various cell lines. Samples were incubated with USP36 Polyclonal antibody (Product # PA5-88995) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          USP36 Antibody in Western Blot (WB)

          Product Details

          PA5-88995

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human USP36 (NP_0793663)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.85 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Wet ice

          RRID

          AB_2805282

          Product Specific Information

          Immunogen sequence: MPIVDKLKEA LKPGRKDSAD DGELGKLLAS SAKKVLLQKI EFEPASKSFS YQLEALKSKY VLLNPKTEGA SRHKSGDDPP ARRQGSEHTY ESCGDGVPAP QKVLFPTERL SLRWERVFRV; Positive Samples: U-87MG, A-431, HeLa; Cellular Location: Nucleus, nucleolus

          Target Information

          May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4).

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Deubiquitinating enzyme 36; Ubiquitin carboxyl-terminal hydrolase 36; ubiquitin specific protease 36; Ubiquitin thioesterase 36; ubiquitin thiolesterase 36; Ubiquitin-specific-processing protease 36

          View more View less

          Gene Aliases: 2700002L06Rik; DUB1; KIAA1453; mKIAA1453; USP36

          View more View less

          UniProt ID: (Human) Q9P275, (Mouse) B1AQJ2

          View more View less

          Entrez Gene ID: (Human) 57602, (Mouse) 72344

          View more View less

          Function(s)
          thiol-dependent ubiquitin-specific protease activity poly(A) RNA binding cysteine-type endopeptidase activity peptidase activity cysteine-type peptidase activity hydrolase activity thiol-dependent ubiquitinyl hydrolase activity
          Process(es)
          ubiquitin-dependent protein catabolic process protein deubiquitination regulation of mitophagy positive regulation of protein targeting to mitochondrion proteolysis proteasome-mediated ubiquitin-dependent protein catabolic process regulation of proteasomal protein catabolic process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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