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FIGURE: 1 / 1
Positive test controls include: HepG2, HT-29, HeLa, A375, Mouse lung, Rat brain. The target is usually found in the following locations: Cytoplasm, Nucleus.
Immunogen sequence: MAPRLQLEKA AWRWAETVRP EEVSQEHIET AYRIWLEPCI RGVCRRNCKG NPNCLVGIGE HIWLGEIDEN SFHNIDDPNC ERRKKNSFVG LTNLGATCYV NTFLQVWFLN LELRQALYLC PSTCSDYMLG DGIQEEKDYE PQTICEHLQY LFALLQNSNR RYIDPSGFVK ALGLDTGQQQ DAQEFSKLFM SLLEDTLSKQ KNPDVRNIVQ QQFCGEYAYV TVCNQCGRES KLLSKFYELE LNIQGHKQLT DCISEFLKEE KLEGDNRYFC ENCQSKQNAT RKIRLLSLPC TLNLQLMRFV
USP48 is a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
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Protein Aliases: Deubiquitinating enzyme 48; Synaptic ubiquitin-specific protease; synUSP; Ubiquitin carboxyl-terminal hydrolase 48; ubiquitin specific protease 31; ubiquitin specific protease 48; Ubiquitin thioesterase 48; ubiquitin thiolesterase 48; Ubiquitin-specific peptidase 48; Ubiquitin-specific protease 48; Ubiquitin-specific-processing protease 48
Gene Aliases: 2810449C13Rik; AI115503; BC021769; D330022K21Rik; Kiaa4202; RAP1GA1; synUSP; USP31; USP48
UniProt ID: (Human) Q86UV5, (Rat) Q76LT8, (Mouse) Q3V0C5
Entrez Gene ID: (Human) 84196, (Rat) 362636, (Mouse) 170707
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