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Invitrogen
USP6NL Polyclonal Antibody
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FIGURE: 1 / 1
USP6NL Antibody (PA5-75944) in WB
Western blot analysis of USP6NL in Lane 1: Jurkat whole cell lysate (40 µg), Lane 2: PC12 whole cell lysate (40 µg), Lane 3: RAW264.7 whole cell lysate (40 µg). Samples were incubated with USP6NL polyclonal antibody (Product # PA5-75944) at a dilution of 1:500.
Product Details
PA5-75944
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 446-491 of Human USP6NL.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719672
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: novel TBC domain containing protein; Related to the N-terminus of tre; RN-tre; USP6 N-terminal-like protein
Gene Aliases: AI316785; KIAA0019; mKIAA0019; RNTRE; TRE2NL; USP6NL; USP6NL-IT1
UniProt ID: (Human) Q92738, (Mouse) Q80XC3
Entrez Gene ID: (Human) 9712, (Rat) 291309, (Mouse) 98910
intracellular protein transport
Golgi organization
virion assembly
regulation of vesicle fusion
retrograde transport, plasma membrane to Golgi
plasma membrane to endosome transport
activation of GTPase activity
regulation of cilium assembly
regulation of Golgi organization
positive regulation of GTPase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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