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1 µg/mL of PA5-77786 was sufficient for detection of UT-A1 in 20 µg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.|Detects approximately 97 and 127kDa.
UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ16167; hUT-A6; HUT2; MGC119566; MGC119567; plasma membrane urea transporter; solute carrier family 14 (urea transporter), member 2, variant 4; solute carrier family 14 (urea transporter), member 2T; Solute carrier family 14 member 2; solute carrier family 14, member 2; testName; urea transport protein; Urea transporter 2; Urea transporter, kidney; UT1; UTA; UTA1; UTR
Gene Aliases: Slc14a2; Slc14a2_v4; Slc14a2T; testSymbol; UrT1-C; UrT1-D; UT-A1; UT-A3; Ut2
UniProt ID: (Rat) Q62668, (Mouse) Q8R4T9
Entrez Gene ID: (Rat) 54302, (Mouse) 27411
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