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Invitrogen
UTS2 Polyclonal Antibody
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UTS2 Antibody (PA5-102735) in IHC (P)
Immunohistochemistry analysis of UTS2 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with UTS2 polyclonal antibody (Product # PA5-102735) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-102735
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human UTS2(Accession O95399), corresponding to amino acid residues Q88-V124.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2852126
Product Specific Information
Antibody detects endogenous levels of total UTS2.
Target Information
Urotensin II is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: prepro U-II; U-II; UII; urocortin 2; Urotensin II; Urotensin-2; urotensin-II
Gene Aliases: PRO1068; U-II; UCN2; UII; UNQ525/PRO1068; UTS2
UniProt ID: (Human) O95399, (Rat) Q9QZQ4
Entrez Gene ID: (Human) 10911, (Rat) 29180
response to hypoxia
negative regulation of glomerular filtration
muscle contraction
positive regulation of cytosolic calcium ion concentration
chemical synaptic transmission
regulation of blood pressure
negative regulation of heart rate
positive regulation of heart rate
positive regulation of fibroblast migration
positive regulation of circadian sleep/wake cycle, wakefulness
positive regulation of synaptic transmission, cholinergic
positive regulation of collagen biosynthetic process
response to testosterone
negative regulation of urine volume
negative regulation of renal sodium excretion
response to drug
positive regulation of cell differentiation
positive regulation of angiogenesis
negative regulation of blood pressure
positive regulation of blood pressure
positive regulation of vasodilation
positive regulation of circadian sleep/wake cycle, REM sleep
negative regulation of insulin secretion
positive regulation of fibroblast proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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