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Invitrogen
UTY Polyclonal Antibody
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FIGURE: 1 / 1
UTY Antibody (PA5-117140) in WB
Western blot analysis of UTY in extracts of various cell lines. Samples were incubated with UTY Polyclonal antibody (Product # PA5-117140) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
PA5-117140
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human UTY (NP_0090563)
Conjugate
Form
Liquid
Concentration
3.01 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901770
Product Specific Information
Positive Samples: Mouse kidney, Mouse testis, Mouse liver, Rat kidney
Immunogen sequence: MKSCAVSLTT AAVAFGDEAK KMAEGKASRE SEEESVSLTV EEREALGGMD SRLFGFVRLH EDGARTKTLL
Target Information
UTY encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: histone demethylase UTY; lysine (K)-specific demethylase 6A; lysine-specific demethylase 6A; male-specific histocompatibility antigen H-YDB; ubiquitously transcribed tetratricopeptide repeat gene, X chromosome; ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome; ubiquitously transcribed tetratricopeptide repeat, X chromosome; ubiquitously transcribed TPR protein on the Y chromosome; ubiquitously transcribed Y chromosome tetratricopeptide repeat protein
Gene Aliases: Hydb; mKIAA4057; RGD1565481; Utx; Uty
Entrez Gene ID: (Rat) 100310845, (Mouse) 22290
RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin binding
identical protein binding
metal ion binding
histone demethylase activity (H3-K27 specific)
sulfonate dioxygenase activity
protein binding
oxidoreductase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
dioxygenase activity
histone demethylase activity (H3-K36 specific)
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
in utero embryonic development
neural tube closure
heart morphogenesis
respiratory system process
heart development
biological_process
regulation of gene expression
neural tube development
somite rostral/caudal axis specification
multicellular organism growth
mesodermal cell differentiation
embryonic organ development
notochord morphogenesis
canonical Wnt signaling pathway
histone H3-K27 demethylation
cardiovascular system development
chromatin modification
regulation of chromatin silencing
establishment of protein localization
oxidation-reduction process
histone H3-K36 demethylation
cardiac muscle cell contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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