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Invitrogen
VAMP3 Polyclonal Antibody
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VAMP3 Antibody (PA5-116218) in IHC (P)
Immunohistochemistry (Paraffin) analysis of VAMP3 in formalin fixed and paraffin embedded human pancreas tissue using the VAMP3 Polyclonal Antibody (Product # PA5-116218) at a dilution of 1:10-1:50, followed by peroxidase conjugation of the secondary antibody and DAB staining.
Product Details
PA5-116218
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Zebrafish
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 15-43 amino acids from the Central region of human VAMP3
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900852
Target Information
Synaptobrevins/VAMPs, syntaxins, and the 25-kDa synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CEB; Cellubrevin; Synaptobrevin-3; vamp; VAMP-3; Vesicle-associated membrane protein 3
Gene Aliases: CEB; D130027G05Rik; SYB3; VAMP-3; VAMP3; zgc:86726
UniProt ID: (Human) Q15836, (Mouse) P63024
Entrez Gene ID: (Human) 9341, (Mouse) 22319, (Zebrafish) 415163
positive regulation of receptor recycling
protein complex assembly
transport
vesicle fusion
protein transport
vesicle-mediated transport
calcium ion regulated exocytosis
substrate adhesion-dependent cell spreading
SNARE complex assembly
retrograde transport, endosome to Golgi
Golgi to plasma membrane protein transport
negative regulation of secretion by cell
exocytosis
vesicle docking involved in exocytosis
positive regulation of immunoglobulin secretion
membrane fusion
mucus secretion
regulation of histamine secretion by mast cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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