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Proteintech
VAMP3/Cellubrevin Monoclonal Antibody (1D10D10)
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Product Details
66488-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1D10D10
Immunogen
VAMP3/Cellubrevin Fusion Protein Ag1156 (1-99 aa encoded by BC005941)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSTGPTAAT GSNRRLQQTQ NQVDEVVDIM RVNVDKVLER DQKLSELDDR ADALQAGASQ FETSAAKLKR KYWWKNCEMW AIGITVLVIF IIIIIVWVVS (1-99 aa encoded by BC005941 )
Target Information
Synaptobrevins/VAMPs, syntaxins, and the 25-kDa synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CEB; Cellubrevin; Synaptobrevin-3; vamp; VAMP-3; Vesicle-associated membrane protein 3
Gene Aliases: CEB; D130027G05Rik; SYB3; VAMP-3; VAMP3
UniProt ID: (Human) Q15836, (Mouse) P63024, (Rat) P63025
Entrez Gene ID: (Human) 9341, (Mouse) 22319, (Rat) 29528
positive regulation of receptor recycling
protein complex assembly
transport
vesicle fusion
protein transport
vesicle-mediated transport
calcium ion regulated exocytosis
substrate adhesion-dependent cell spreading
SNARE complex assembly
retrograde transport, endosome to Golgi
Golgi to plasma membrane protein transport
negative regulation of secretion by cell
exocytosis
vesicle docking involved in exocytosis
positive regulation of immunoglobulin secretion
membrane fusion
mucus secretion
regulation of histamine secretion by mast cell
neurotransmitter secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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