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Immunogen sequence: NALRFILNALG EKFVPQPAEE LSPSSPMDAW ILSRLALAAQ ECERGFLTRE LSLVTHALHH FWLHNLCDVY LE
Highest antigen sequence identity to the following orthologs - mouse 85%, rat 85%.
This gene encodes a mitochondrial aminoacyl-tRNA synthetase, which catalyzes the attachment of valine to tRNA(Val) for mitochondrial translation. Mutations in this gene cause combined oxidative phosphorylation deficiency-20, and are also associated with early-onset mitochondrial encephalopathies. Alternative splicing of this gene results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: valine tRNA ligase 2, mitochondrial (putative); Valine--tRNA ligase, mitochondrial; ValRS; valyl trna synthetase; Valyl-tRNA synthetase; valyl-tRNA synthetase like; Valyl-tRNA synthetase-like
Gene Aliases: COXPD20; KIAA1885; VALRS; VARS2; VARS2L; VARSL
UniProt ID: (Human) F5GXJ0
Entrez Gene ID: (Human) 57176
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