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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • VDAC1/VDAC2 Antibodies

          Proteintech

          VDAC1/2 Polyclonal Antibody

          137 References
          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite VDAC1/2 Polyclonal Antibody

          • Antibody Testing Data (19)
          VDAC1/2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          VDAC1/2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 19

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          VDAC1/2 Antibody (10866-1-AP) in ICC/IF

          Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 10866-1-AP (VDAC1/Porin antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          VDAC1/2 Antibody in Immunocytochemistry (ICC/IF)
          VDAC1/2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          VDAC1/2 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Western Blot (WB)
          VDAC1/2 Antibody in Immunoprecipitation (IP)

          Product Details

          10866-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 119 publications 119 publications

          Immunohistochemistry (IHC)

          -
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:50
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 10 publications 10 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 4 publications 4 publications

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Insect, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          VDAC1/2 Fusion Protein Ag1144 (1-283 aa encoded by BC008482)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.21 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This polyclonal antibody raised against full-length human VDAC1 protein can cross react with VDAC2.

          Immunogen sequence: MAVPPTYAD LGKSARDVFT KGYGFGLIKL DLKTKSENGL EFTSSGSANT ETTKVTGSLE TKYRWTEYGL TFTEKWNTDN TLGTEITVED QLARGLKLTF DSSFSPNTGK KNAKIKTGYK REHINLGCDM DFDIAGPSIR GALVLGYEGW LAGYQMNFET AKSRVTQSNF AVGYKTDEFQ LHTNVNDGTE FGGSIYQKVN KKLETAVNLA WTAGNSNTRF GIAAKYQIDP DACFSAKVNN SSLIGLGYTQ TLKPGIKLTL SALLDGKNVN AGGHKLGLGL EFQA (1-283 aa encoded by BC008482)

          Target Information

          This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: B36-VDAC; mVDAC1; mVDAC5; Non-selective voltage-gated ion channel VDAC1; Non-selective voltage-gated ion channel VDAC2; Outer mitochondrial membrane protein porin 1; Outer mitochondrial membrane protein porin 2; Plasmalemmal porin; Porin 31HL; Porin 31HM; rVDAC1; VDAC-1; VDAC-2; VDAC-5; VDAC-6; voltage-dependent anion channel 2; Voltage-dependent anion-selective channel protein 1; voltage-dependent anion-selective channel protein 2; Voltage-dependent anion-selective channel protein 5; Voltage-dependent anion-selective channel protein 6

          View more View less

          Gene Aliases: AL033343; mVDAC2; mVDAC6; POR; PORIN; VDAC; VDAC-1; VDAC1; VDAC2; Vdac5; Vdac6

          View more View less

          UniProt ID: (Human) P21796, (Human) P45880, (Mouse) Q60932, (Rat) Q9Z2L0, (Mouse) Q60930, (Rat) P81155

          View more View less

          Entrez Gene ID: (Human) 7416, (Human) 7417, (Mouse) 22333, (Rat) 83529, (Mouse) 22334, (Rat) 83531

          View more View less

          Function(s)
          protein binding voltage-gated anion channel activity porin activity protein kinase binding protein complex binding ion channel binding nucleotide binding anion channel activity
          Process(es)
          behavioral fear response transport ion transport anion transport mitochondrial calcium ion transport apoptotic process chemical synaptic transmission neuron-neuron synaptic transmission learning regulation of anion transport transmembrane transport anion transmembrane transport regulation of anion transmembrane transport negative regulation of protein polymerization negative regulation of intrinsic apoptotic signaling pathway epithelial cell differentiation ion transmembrane transport regulation of ion transmembrane transport viral process macroautophagy regulation of mitophagy negative regulation of reactive oxygen species metabolic process
          It has to be done as per old AB suggested Products section.
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