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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • VDAC Antibodies

          Proteintech

          VDAC1/Porin Polyclonal Antibody

          110 References
          View all (29) VDAC antibodies
          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite VDAC1/Porin Polyclonal Antibody

          • Antibody Testing Data (19)
          VDAC1/Porin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          VDAC1/Porin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 19

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          VDAC1/Porin Antibody (55259-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded Human heart tissue slide using (Product # 55259-1-AP) VDAC1/Porin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          VDAC1/Porin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/Porin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/Porin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/Porin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/Porin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/Porin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VDAC1/Porin Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Western Blot (WB)
          VDAC1/Porin Antibody in Flow Cytometry (Flow)
          VDAC1/Porin Antibody in Immunoprecipitation (IP)

          Product Details

          55259-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:6,000
          View 90 publications 90 publications

          Immunohistochemistry (IHC)

          -
          View 4 publications 4 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:200
          -

          Immunocytochemistry (ICC/IF)

          -
          View 6 publications 6 publications

          Flow Cytometry (Flow)

          0.2 µg/1x10^6 cells
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 5 publications 5 publications

          in situ PLA (PLA)

          -
          View 1 publication 1 publication

          Not applicable (N/A)

          -
          View 3 publications 3 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Dog, Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.31 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This antibody is specific to VDAC1.

          Target Information

          Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC constitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: hVDAC1; MGC111064; Mitochondrial Porin; mVDAC1; mVDAC5; Non-selective voltage-gated ion channel VDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; PORIN-31-HL; rVDAC1; VD; VDAC-1; VDAC-5; Voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 5

          View more View less

          Gene Aliases: AL033343; PORIN; VDAC; VDAC-1; VDAC1; Vdac5

          View more View less

          UniProt ID: (Human) P21796, (Mouse) Q60932, (Rat) Q9Z2L0

          View more View less

          Entrez Gene ID: (Human) 7416, (Mouse) 22333, (Rat) 83529

          View more View less

          Function(s)
          protein binding voltage-gated anion channel activity porin activity protein kinase binding protein complex binding ion channel binding nucleotide binding anion channel activity
          Process(es)
          behavioral fear response transport ion transport anion transport mitochondrial calcium ion transport apoptotic process chemical synaptic transmission neuron-neuron synaptic transmission learning regulation of anion transport transmembrane transport anion transmembrane transport regulation of anion transmembrane transport epithelial cell differentiation ion transmembrane transport regulation of ion transmembrane transport viral process macroautophagy regulation of mitophagy negative regulation of reactive oxygen species metabolic process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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