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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • VE-cadherin (CD144) Antibodies

          Invitrogen

          VE-cadherin Polyclonal Antibody

          24 Published Figures
          43 References
          View all (56) VE-cadherin (CD144) antibodies

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          Datasheet
          Protocols
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          Datasheet
          Protocols
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          Cite VE-cadherin Polyclonal Antibody

          • Antibody Testing Data (3)
          • Published Figures (24)
          VE-cadherin Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          VE-cadherin Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 27

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          VE-cadherin Antibody (36-1900) in ICC/IF

          Immunofluorescent analysis of VE-Cadherin (green) in Huvec cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.1% Triton X-100 in PBS for 10 minutes, and blocked with 3% BSA in PBS (Product # 37525) for 30 minutes at room temperature. Cells were stained with a VE-Cadherin polyclonal antibody (Product # 36-1900) at a dilution of 10 µg/mL in blocking buffer for 1 hour at ... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          VE-cadherin Antibody in Immunocytochemistry (ICC/IF)
          VE-cadherin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Immunohistochemistry (IHC)
          VE-cadherin Antibody in Immunocytochemistry (ICC/IF)
          VE-cadherin Antibody in Immunocytochemistry (ICC/IF)
          VE-cadherin Antibody in Immunocytochemistry (ICC/IF)
          VE-cadherin Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)
          VE-cadherin Antibody in Immunohistochemistry (IHC)
          VE-cadherin Antibody in Immunohistochemistry (IHC)
          VE-cadherin Antibody in Immunohistochemistry (IHC)
          VE-cadherin Antibody in Immunohistochemistry (IHC)
          VE-cadherin Antibody in Immunohistochemistry (IHC)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)
          VE-cadherin Antibody in Western Blot (WB)

          Product Details

          36-1900

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-3 µg/mL
          View 15 publications 15 publications

          Immunohistochemistry (IHC)

          -
          View 12 publications 12 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:10-1:50
          -

          Immunocytochemistry (ICC/IF)

          5-10 µg/mL
          View 15 publications 15 publications

          ELISA (ELISA)

          0.1-1 µg/mL
          -

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rabbit, Rat, Sheep

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide derived from a C-terminal region of the human VE-cadherin (vascular endothelial cadherin, cadherin-5, CD144) protein.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.25 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.4

          Contains

          0.1% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2533243

          Product Specific Information

          This antibody has been successfully used in western blot, immunofluorescence, immunohistochemistry, and ELISA.

          Target Information

          VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: 7B4 antigen; 7B4/cadherin-5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); Cadherin-5; CD144; cd144 antigen; endothelial-specific cadherin; Vascular endothelial cadherin; VE-cadherin

          View more View less

          Gene Aliases: 7B4; AA408225; CD144; CDH5; VE-Cad; Vec; VEcad; VECD

          View more View less

          UniProt ID: (Human) P33151, (Mouse) P55284

          View more View less

          Entrez Gene ID: (Human) 1003, (Mouse) 12562, (Rat) 307618

          View more View less

          Function(s)
          receptor binding calcium ion binding protein binding beta-catenin binding protein phosphatase binding ion channel binding metal ion binding
          Process(es)
          blood vessel maturation cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules negative regulation of cell proliferation single organismal cell-cell adhesion regulation of establishment of cell polarity cell-cell junction assembly transforming growth factor beta receptor signaling pathway adherens junction organization positive regulation of establishment of endothelial barrier
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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