VEGF-164 Monoclonal Antibody (123704)

fibronectin binding receptor binding cytokine activity platelet-derived growth factor receptor binding vascular endothelial growth factor receptor binding growth factor activity heparin binding neuropilin binding chemoattractant activity identical protein binding protein homodimerization activity vascular endothelial growth factor receptor 1 binding vascular endothelial growth factor receptor 2 binding protein heterodimerization activity receptor agonist activity extracellular matrix binding

negative regulation of transcription from RNA polymerase II promoter angiogenesis ovarian follicle development blood vessel development patterning of blood vessels response to hypoxia in utero embryonic development kidney development positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation vasculature development lymphangiogenesis blood vessel remodeling sprouting angiogenesis cell migration involved in sprouting angiogenesis positive regulation of neuroblast proliferation positive regulation of mesenchymal cell proliferation positive regulation of receptor internalization basophil chemotaxis heart morphogenesis outflow tract morphogenesis coronary vein morphogenesis regulation of transcription from RNA polymerase II promoter nervous system development mesoderm development female pregnancy aging lactation cell proliferation positive regulation of cell proliferation regulation of cell shape response to cold positive regulation of signal transduction positive regulation of endothelial cell migration positive regulation of gene expression cell migration negative regulation of cell-cell adhesion cell differentiation hyaluronan metabolic process monocyte differentiation macrophage differentiation lung development positive regulation of cell migration regulation of cGMP metabolic process epithelial cell differentiation positive regulation of vascular endothelial growth factor receptor signaling pathway post-embryonic camera-type eye development positive regulation of protein complex assembly positive regulation of protein autophosphorylation activation of protein kinase activity response to estradiol response to progesterone positive regulation of CREB transcription factor activity positive regulation of peptidyl-serine phosphorylation response to vitamin A tube formation cellular response to drug endothelial cell chemotaxis cellular response to vascular endothelial growth factor stimulus lymph vessel morphogenesis positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway vascular endothelial growth factor signaling pathway positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway VEGF-activated neuropilin signaling pathway growth wound healing T-helper 1 type immune response eye photoreceptor cell development negative regulation of apoptotic process negative regulation of programmed cell death positive regulation of vascular permeability surfactant homeostasis negative regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of MAP kinase activity negative regulation of neuron apoptotic process positive regulation of blood vessel endothelial cell migration endothelial cell migration cellular response to fibroblast growth factor stimulus regulation of endothelial cell differentiation positive regulation of angiogenesis negative regulation of bone resorption positive regulation of cell adhesion positive regulation of transcription from RNA polymerase II promoter vascular endothelial growth factor receptor signaling pathway mRNA stabilization lung alveolus development cell maturation blood vessel morphogenesis camera-type eye morphogenesis positive regulation of smooth muscle cell proliferation neuron development cardiac muscle fiber development branching morphogenesis of an epithelial tube positive regulation of axon extension involved in axon guidance artery morphogenesis positive regulation of epithelial cell proliferation positive regulation of peptidyl-tyrosine phosphorylation positive chemotaxis positive regulation of positive chemotaxis induction of positive chemotaxis positive regulation of cellular component movement response to folic acid positive regulation of cell division positive regulation of focal adhesion assembly positive regulation of protein kinase B signaling primitive erythrocyte differentiation cell chemotaxis lung vasculature development mammary gland alveolus development positive regulation of mast cell chemotaxis cardiac vascular smooth muscle cell development angiogenesis involved in coronary vascular morphogenesis coronary artery morphogenesis positive regulation of transcription from RNA polymerase II promoter in response to hypoxia positive regulation of ERK1 and ERK2 cascade response to oxygen levels cellular response to hypoxia dopaminergic neuron differentiation response to dexamethasone cellular response to dexamethasone stimulus commissural neuron axon guidance positive regulation of protein kinase C signaling positive regulation of cell migration involved in sprouting angiogenesis positive regulation of branching involved in ureteric bud morphogenesis regulation of retinal ganglion cell axon guidance positive regulation of peptidyl-tyrosine autophosphorylation positive regulation of p38MAPK cascade negative regulation of neuron death positive regulation of lymphangiogenesis regulation of hematopoietic progenitor cell differentiation positive regulation of histone deacetylase activity positive regulation of retinal ganglion cell axon guidance positive regulation of protein localization to early endosome positive regulation of protein kinase D signaling negative regulation of extrinsic apoptotic signaling pathway