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Invitrogen
VMAT2 Polyclonal Antibody
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VMAT2 Antibody (PA5-22864) in IHC
Immunohistochemistry analysis of VMAT2 was performed on human H1 huES teratoma tissue. To expose target proteins, antigen retrieval was performed using a pressure cooker in 10mM citric acid (pH 6.0). Following antigen retrieval, endogenous peroxidases were blocked with 2.5% hydrogen peroxide. Tissue slide was successively blocked with Avidin D, biotin and protein blocking buffer. Tissues were probed with a VMAT2 polyclonal antibody (Product # PA5-22864) diluted 1:100 overnight at 4°C. After washing tissue slide was incubated with biotinyla... View More
Product Details
PA5-22864
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rabbit,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Reacts with an internal sequence of the human, mouse and rat VMAT2 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11154073
Target Information
VMAT2 is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. It is a requisite for vesicular amine storage prior to secretion via exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC120477; MGC120478; MGC26538; monoamine neurotransmitter transporter; Monoamine transporter; solute carrier family 18 (vesicular monoamine transporter), member 2; solute carrier family 18 (vesicular monoamine), member 2; Solute carrier family 18 A2 (vesicular monoamine transporter 2); Solute carrier family 18 member 2; solute carrier family 18, member 2; Synaptic vesicular amine transporter; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; Vesicular monoamine transporter 2
Gene Aliases: 1110037L13Rik; 9330105E13; MNAT; SLC18A2; SVAT; SVMT; VAT2; VMAT-2; VMAT2
UniProt ID: (Human) Q05940, (Mouse) Q8BRU6, (Rat) Q01827
Entrez Gene ID: (Human) 6571, (Mouse) 214084, (Rat) 25549
response to amphetamine
transport
neurotransmitter transport
serotonin transport
aging
locomotory behavior
response to toxic substance
post-embryonic development
organic cation transport
aminergic neurotransmitter loading into synaptic vesicle
monoamine transport
drug transport
obsolete death
insulin secretion
cellular response to drug
glucose homeostasis
negative regulation of neurotransmitter transport
transmembrane transport
ammonium transmembrane transport
chemical synaptic transmission
neurotransmitter secretion
response to herbicide
response to zinc ion
dopamine transport
endocytic recycling
sequestering of neurotransmitter
response to cocaine
response to starvation
response to corticosterone
cellular response to ammonium ion
neurotransmitter loading into synaptic vesicle
negative regulation of reactive oxygen species biosynthetic process
drug transmembrane transport
response to metal ion
response to drug
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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