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Invitrogen
VNN3 Polyclonal Antibody
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Product Details
PA5-34459
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 19 amino acid synthetic peptide near the carboxy terminus of human VNN3
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551811
Product Specific Information
A suggested positive control is human brain tissue lysate.
PA5-34459 can be used with blocking peptide PEP-1501.
Target Information
The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: pantetheinase pseudogene; pantetheinase-associated gene expressed in leukocytes (PAGEL)-alpha; vanin 1 pseudogene; Vanin-3; Vascular non-inflammatory molecule 3
Gene Aliases: HSA238982; RGD1560609; Vnn3
UniProt ID: (Mouse) Q9QZ25
Entrez Gene ID: (Human) 55350, (Rat) 498992, (Mouse) 26464
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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