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VPAC1 (VIPR1) (extracellular) Antibody (AVR-001-200UL) in ICC/IF
Expression of VPAC1 in human HT-29 cells - Cell surface detection of VPAC1 in live intact human HT-29 colorectal adenocarcinoma cells. A. Extracellular staining of live cells with Anti-VPAC1 (VIPR1) (extracellular) Antibody (#AVR-001), (1:25), followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody (red). B. Cell nuclei were visualized using Hoechst 33342 (blue). C. Live view of the cells.
Product Details
AVR-001-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)EEAQLENETIG(S)SK, corresponding to amino acid residues 52-65 of human VPAC1, Extracellular, N-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
The Vasoactive Intestinal Polypeptide Receptor 1 (VPAC1) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. Together, the VPAC1 and VPAC2 receptors compose a subtype of the VIP receptor. Expression of the VIP and PACAP receptors has been linked to the presence of human tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Pacap receptor; PACAP type II receptor; PACAP-R-2; PACAP-R2; pituitary adenylate cyclase activating polypeptide receptor, type II; Pituitary adenylate cyclase-activating polypeptide type II receptor; Pvr2; type 1 vasoactive intestinal peptide receptor; Vasoactive intestinal polypeptide receptor 1; Vasopressive intestinal peptide receptor; VIP and PACAP receptor 1; VIP receptor 1; VIP receptor subtype 1; VIP receptor, type I; VIP-R-1; VIP1 receptor; VPAC1 receptor; VPAC1R
Gene Aliases: AV071699; HVR1; II; PACAP-R-2; PACAP-R2; RATVASREC; RDC1; V1RG; VAPC1; VASREC; VIP-R-1; VIP-R1; VIPR; VIPR1; VIRG; VPAC1; VPAC1R; VPCAP1R
UniProt ID: (Human) P32241, (Rat) P30083, (Mouse) P97751
Entrez Gene ID: (Human) 7433, (Rat) 24875, (Mouse) 22354
G-protein coupled receptor signaling pathway
muscle contraction
immune response
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
chemical synaptic transmission
digestion
positive regulation of cell proliferation
signal transduction
Performance Guarantee
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