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PA3-114 detects VPAC2 Receptor in human samples.
PA3-114 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures. By Western blot, this antibody detects an ~50-65 kDa protein representing VPAC2 Receptor in human samples. In immunohistochemistry, VPAC2 receptor immunoreactivity is predominantly localized to neuroendocrine cells.
PA3-114 immunogen is a synthetic peptide, conjugated to KLH, corresponding to the residues L(419) Q F H R G S R A Q S F L Q T E T S V I(438) of human VPAC2 receptor.
The Vasoactive Intestinal Polypeptide Receptor 2 (VPAC2) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. Together, the VPAC1 and VPAC2 receptors compose a subtype of the VIP receptor. Expression of the VIP and PACAP receptors has been linked to the presence of human tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Helodermin-preferring VIP receptor; PACAP type III receptor; Pacap type-3; PACAP3; PACAPR-3; Pituitary adenylate cyclase-activating polypeptide type III receptor; Pvr3; SCZD16; tcag7.970; Vasoactive intestinal polypeptide receptor 2; VIP and PACAP receptor 2; Vip type-2 receptor; VIP-R-2; Vip-r2; Vip2 receptor; VPAC2 receptor; VPAC2R
Gene Aliases: C16DUPq36.3; DUP7q36.3; PACAP-R-3; PACAP-R3; VIP-R-2; VIP2R; VIPR2; VPAC2; VPAC2R; VPCAP2R
UniProt ID: (Human) P41587
Entrez Gene ID: (Human) 7434
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