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Invitrogen
VPS28 Monoclonal Antibody (OTI1A8)
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Product Details
MA5-26189
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1A8
Immunogen
Full length human recombinant protein of VPS28 produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2725665
Target Information
This gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. The encoded protein is one of the three subunits of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. The two other subunits of ESCRT-I are vesicular protein sorting 23, also known as tumor susceptibility gene 101 (TSG101), and vesicular protein sorting 37. Two alternative transcripts encoding different isoforms have been described. Additional alternative transcripts may exist but the proteins encoded by these transcripts have not been verified experimentally.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Caspase-activated DNase inhibitor that interacts with ASK1; CIIA; ESCRT-I complex subunit VPS28; H-Vps28; MGC60323; vacuolar protein sorting 28 homolog; vacuolar protein sorting 28-like protein; Vacuolar protein sorting-associated protein 28 homolog; yeast class E protein Vps28p homolog
Gene Aliases: 1110014J03Rik; CIIA; D730005C08Rik; VPS28
UniProt ID: (Human) Q9UK41, (Mouse) Q9D1C8
Entrez Gene ID: (Dog) 607677, (Human) 51160, (Mouse) 66914, (Rat) 300052
autophagy
endosomal transport
viral life cycle
negative regulation of protein ubiquitination
multivesicular body assembly
viral budding via host ESCRT complex
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
positive regulation of protein catabolic process
intracellular transport of virus
positive regulation of ubiquitin-dependent endocytosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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