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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • VPS39 Antibodies

          Invitrogen

          VPS39 Polyclonal Antibody

          1 Published Figure
          2 References
          View all (7) VPS39 antibodies

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          Cite VPS39 Polyclonal Antibody

          • Antibody Testing Data (4)
          • Published Figures (1)
          VPS39 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.
          VPS39 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          VPS39 Antibody (PA5-21104) in IHC

          Immunofluorescence of VPS39 in human liver tissue with VPS39 Polyclonal Antibody (Product # PA5-21104) at 5 µg/mL. Green: VPS39 Red: Phylloidin staining Blue: DAPI staining {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          VPS39 Antibody in Immunohistochemistry (IHC)
          VPS39 Antibody in Immunohistochemistry (IHC)
          VPS39 Antibody in Immunohistochemistry (IHC)
          VPS39 Antibody in Western Blot (WB)
          VPS39 Antibody in Western Blot, Immunoprecipitation (WB, IP)

          Product Details

          PA5-21104

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.5 µg/mL
          View 1 publication 1 publication

          Immunohistochemistry (IHC)

          5 µg/mL
          -

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          An 18 amino acid peptide near the carboxy terminus of human VPS39.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS

          Contains

          0.02% sodium azide

          Storage conditions

          Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_11152911

          Product Specific Information

          A suggested positive control is rat liver tissue lysate.

          PA5-21104 can be used with blocking peptide PEP-1218.

          Target Information

          VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6. 5.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: hVam6p; OTTMUSP00000023341; OTTMUSP00000023350; PI3K type 3; TRAP1-like protein; vacuolar protein sorting 39 homolog; Vam6; Vam6/Vps39-like protein; VPS39 HOPS complex subunit

          View more View less

          Gene Aliases: A230065P22Rik; AW743070; hVam6p; KIAA0770; mVam6; Pldn; TLP; VAM6; Vam6P; VPS39

          View more View less

          UniProt ID: (Human) Q96JC1, (Mouse) Q8R5L3

          View more View less

          Entrez Gene ID: (Human) 23339, (Rat) 362199, (Mouse) 269338

          View more View less

          Function(s)
          protein binding
          Process(es)
          intracellular protein transport vesicle-mediated transport regulation of catalytic activity transport protein transport autophagy endosome to lysosome transport endosomal vesicle fusion vacuole fusion late endosome to lysosome transport retrograde transport, endosome to plasma membrane
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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