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VPS45A Antibody (BS-12777R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with VPS45 Polyclonal Antibody, Unconjugated (bs-12777R) at 1:400 overnight at 4°C, DAB staining.
Product Details
BS-12777R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human VPS45A, amino acids 401-500.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: h-VPS45; HGNC:14579; hlVps45; leucocyte vacuolar protein sorting 45; mVps45; RP11-458I7.2; rVps45; vacuolar protein sorting 45A; vacuolar protein sorting protein 45; Vacuolar protein sorting-associated protein 45; vesicular transport protein rvps45
Gene Aliases: AI462172; AW554165; H1; H1VPS45; mVps45; SCN5; VPS45; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
UniProt ID: (Human) Q9NRW7, (Mouse) P97390, (Rat) O08700
Entrez Gene ID: (Human) 11311, (Mouse) 22365, (Rat) 64516
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