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          • Primary Antibodies ›
          • VRK1 Antibodies

          Abnova

          VRK1 Polyclonal Antibody, MaxPab™

          View all (18) VRK1 antibodies

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          Cite VRK1 Polyclonal Antibody, MaxPab™

          • Antibody Testing Data (2)
          VRK1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          VRK1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          VRK1 Antibody (H00007443-D01P) in WB

          Western Blot analysis of VRK1 expression in transfected 293T cell line (H00007443-T02) by VRK1 MaxPab polyclonal antibody.

          Lane 1: VRK1 transfected lysate(45.50 KDa).
          Lane 2: Non-transfected lysate.
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          VRK1 Antibody in Western Blot (WB)
          VRK1 Antibody in Western Blot (WB)

          Product Details

          H00007443-D01P

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          VRK1 (NP_003375.1, 1 a.a. approximately 396 a.a) full-length human protein.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          See Label

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Sequence of this protein is as follows: MPRVKAAQAG RQSSAKRHLA EQFAVGEIIT DMAKKEWKVG LPIGQGGFGC IYLADMNSSE SVGSDAPCVV KVEPSDNGPL FTELKFYQRA AKPEQIQKWI RTRKLKYLGV PKYWGSGLHD KNGKSYRFMI MDRFGSDLQK IYEANAKRFS RKTVLQLSLR ILDILEYIHE HEYVHGDIKA SNLLLNYKNP DQVYLVDYGL AYRYCPEGVH KEYKEDPKRC HDGTIEFTSI DAHNGVAPSR RGDLEILGYC MIQWLTGHLP WEDNLKDPKY VRDSKIRYRE NIASLMDKCF PEKNKPGEIA KYMETVKLLD YTEKPLYENL RDILLQGLKA IGSKDDGKLD LSVVENGGLK AKTITKKRKK EIEESKEPGV EDTEWSNTQT EEAIQTRSRT RKRVQK

          Target Information

          Human vaccinia-related kinase 1 (VRK1) is a new kinase related to a poxvirus kinase, and more distantly to the casein kinase 1 family. VRK1 shows strong autophosphorylating activity in several Ser and Thr residues. VRK has also been found to be an upstream regulator of p53 that belongs to a new signaling pathway.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: MGC117401; MGC138280; Serine/threonine-protein kinase VRK1; vaccinia virus B1R-related kinase 1; Vaccinia-related kinase 1

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          Gene Aliases: PCH1; PCH1A; VRK1

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          UniProt ID: (Human) Q99986

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          Entrez Gene ID: (Human) 7443

          View more View less

          Function(s)
          protein kinase activity protein serine/threonine kinase activity protein binding ATP binding protein kinase binding nucleosomal histone binding histone kinase activity (H3-S10 specific) histone kinase activity (H3-T3 specific)
          Process(es)
          protein phosphorylation mitotic nuclear division mitotic nuclear envelope disassembly mitotic nuclear envelope reassembly regulation of cell shape histone H3-S10 phosphorylation protein autophosphorylation cell division histone H3-T3 phosphorylation Golgi disassembly
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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