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Recommended positive controls: HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (85%), Rat (86%), Pig (86%), Rhesus Monkey (98%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Human vaccinia-related kinase 1 (VRK1) is a new kinase related to a poxvirus kinase, and more distantly to the casein kinase 1 family. VRK1 shows strong autophosphorylating activity in several Ser and Thr residues. VRK has also been found to be an upstream regulator of p53 that belongs to a new signaling pathway.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MGC117401; MGC138280; Serine/threonine-protein kinase VRK1; vaccinia virus B1R-related kinase 1; Vaccinia-related kinase 1
Gene Aliases: PCH1; PCH1A; VRK1
UniProt ID: (Human) Q99986
Entrez Gene ID: (Human) 7443
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