Proteintech

VTI1A Polyclonal Antibody

VTI1A Antibody in Immunocytochemistry (ICC/IF)

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VTI1A Antibody (12354-1-AP) in ICC/IF

Immunofluorescent analysis of NIH/3T3 cells using 12354-1-AP (VTI1A antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IGG.

VTI1A Antibody in Immunoprecipitation (IP)

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Product Details

12354-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 7 publications 7 publications

Immunocytochemistry (ICC/IF)

1:10-1:100

View 3 publications 3 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

VTI1A Fusion Protein Ag3018 (1-203 aa encoded by BC017052)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSSDFEGYE QDFAVLTAEI TSKIARVPRL PPDEKKQMVA NVEKQLEEAK ELLEQMDLEV REIPPQSRGM YSNRMRSYKQ EMGKLETDFK RSRIAYSDEV RNELLGDDGN SSENQRAHLL DNTERLERSS RRLEAGYQIA VETEQIGQEM LENLSHDREK IQRARERLRE TDANLGKSSR ILTGMLRRGC SVKKQCNLSL APKA (1-203 aa encoded by BC017052)

Target Information

V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non- conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Nanoelectrochemistry reveals how soluble Aβ₄₂ oligomers alter vesicular storage and release of glutamate.

Proceedings of the National Academy of Sciences of the United States of America

Yang XK,Zhang FL,Jin XK,Jiao YT,Zhang XW,Liu YL,Amatore C,Huang WH

Tue May 09 00:00:00 UTC 2023

Generation of GLA-Knockout Human Embryonic Stem Cell Lines to Model Autophagic Dysfunction and Exosome Secretion in Fabry Disease-Associated Hypertrophic Cardiomyopathy.

Cells

Song HY,Chien CS,Yarmishyn AA,Chou SJ,Yang YP,Wang ML,Wang CY,Leu HB,Yu WC,Chang YL,Chiou SH

Mon Apr 08 00:00:00 UTC 2019

Phosphoproteomics reveals that the hVPS34 regulated SGK3 kinase specifically phosphorylates endosomal proteins including Syntaxin-7, Syntaxin-12, RFIP4 and WDR44.

The Biochemical journal

Malik N,Nirujogi RS,Peltier J,Macartney T,Wightman M,Prescott AR,Gourlay R,Trost M,Alessi DR,Karapetsas A

Wed Oct 30 00:00:00 UTC 2019

Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.

Oncotarget

Huo Y,Zheng Z,Chen Y,Wang Q,Zhang Z,Deng H

Tue Jul 19 00:00:00 UTC 2016

Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.

Oncotarget

Huo Y,Zheng Z,Chen Y,Wang Q,Zhang Z,Deng H

Tue Jul 19 00:00:00 UTC 2016

Deficiency of the Cog8 subunit in normal and CDG-derived cells impairs the assembly of the COG and Golgi SNARE complexes.

Traffic (Copenhagen, Denmark)

Laufman O,Freeze HH,Hong W,Lev S

Tue Oct 01 00:00:00 UTC 2013

Deficiency of the Cog8 subunit in normal and CDG-derived cells impairs the assembly of the COG and Golgi SNARE complexes.

Traffic (Copenhagen, Denmark)

Laufman O,Freeze HH,Hong W,Lev S

Tue Oct 01 00:00:00 UTC 2013

Deficiency of the Cog8 subunit in normal and CDG-derived cells impairs the assembly of the COG and Golgi SNARE complexes.

Traffic (Copenhagen, Denmark)

Laufman O,Freeze HH,Hong W,Lev S

Tue Oct 01 00:00:00 UTC 2013

Deficiency of the Cog8 subunit in normal and CDG-derived cells impairs the assembly of the COG and Golgi SNARE complexes.

Traffic (Copenhagen, Denmark)

Laufman O,Freeze HH,Hong W,Lev S

Tue Oct 01 00:00:00 UTC 2013

The COG complex interacts with multiple Golgi SNAREs and enhances fusogenic assembly of SNARE complexes.

Journal of cell science

Laufman O,Hong W,Lev S

Fri Mar 15 00:00:00 UTC 2013

The COG complex interacts with multiple Golgi SNAREs and enhances fusogenic assembly of SNARE complexes.

Journal of cell science

Laufman O,Hong W,Lev S

Fri Mar 15 00:00:00 UTC 2013

The COG complex interacts with multiple Golgi SNAREs and enhances fusogenic assembly of SNARE complexes.

Journal of cell science

Laufman O,Hong W,Lev S

Fri Mar 15 00:00:00 UTC 2013

The COG complex interacts with multiple Golgi SNAREs and enhances fusogenic assembly of SNARE complexes.

Journal of cell science

Laufman O,Hong W,Lev S

Fri Mar 15 00:00:00 UTC 2013

The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport.

The Journal of cell biology

Laufman O,Hong W,Lev S

Mon Aug 08 00:00:00 UTC 2011

The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport.

The Journal of cell biology

Laufman O,Hong W,Lev S

Mon Aug 08 00:00:00 UTC 2011

The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport.

The Journal of cell biology

Laufman O,Hong W,Lev S

Mon Aug 08 00:00:00 UTC 2011

The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport.

The Journal of cell biology

Laufman O,Hong W,Lev S

Mon Aug 08 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: SNARE Vti1a-beta protein; vesicle transport through interaction with t-SNAREs 1 homolog; Vesicle transport through interaction with t-SNAREs homolog 1A; Vesicle transport v-SNARE protein Vti1-like 2; Vti1-rp2

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Gene Aliases: 1110014F16Rik; 1110018K19Rik; 4921537J05Rik; MMDS3; MVti1; MVti1a; Vti1; Vti1-rp2; VTI1A; Vti1l2; VTI1RP2

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UniProt ID: (Human) Q96AJ9, (Mouse) O89116, (Rat) Q9JI51

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Entrez Gene ID: (Human) 143187, (Mouse) 53611, (Rat) 65277

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Function(s)

SNARE binding SNAP receptor activity protein binding

Process(es)

protein targeting to vacuole transport intracellular protein transport ER to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport Golgi to vacuole transport protein transport vesicle-mediated transport retrograde transport, endosome to Golgi vesicle fusion with Golgi apparatus voluntary musculoskeletal movement Golgi ribbon formation autophagy membrane fusion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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VTI1A Polyclonal Antibody

VTI1A Antibody (12354-1-AP) in ICC/IF

Product Details

12354-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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