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Invitrogen
Venezuelan Equine Encephalitis Virus NSP1 Recombinant Rabbit Monoclonal Antibody (HL1593)
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FIGURE: 1 / 2
Venezuelan Equine Encephalitis Virus NSP1 Antibody (MA5-47105) in ICC/IF
Immunocytochemistry analysis of Venezuelan Equine Encephalitis Virus NSP1 in paraffin-embedded mock and Venezuelan equine encephalitis virus nsp1 transfected 293T cell pellet. Green: Venezuelan equine encephalitis virus nsp1 stained by Venezuelan equine encephalitis virus nsp1 monoclonal antibody (Product # MA5-47105) diluted at 1:1,000. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
MA5-47105
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1593
Immunogen
Recombinant protein encompassing a sequence within the center region of Venezuelan equine encephalitis virus nsp1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2938177
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
Venezuelan equine encephalitis virus (VEEV) is a member of genus Alphavirus in the family Togaviridae|VEEV encodes four nonstructural proteins (nsP1, nsP2, nsP3 and nsP4) and five structural proteins (capsid (C), envelope (E) 3, E2, 6k, and E1)|The Nsp1 gene of VEEV contains a 51-nt conserved sequence element (CSE) that is essential for virus replication|Mutation or deletion of CSE results in loss of infectivity of VEEV, probably due to inefficient recognition of the viral RNA core promoter element by the virus replication complex|Nsp1 functions as a methyltransferase and guanylylation enzyme, two properties needed for the 5' capping of VEEV genomic RNA [PMID: 30781656]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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