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WARS Antibody (A304-275A) in IHC (P)
Detection of human WARS by immunohistochemistry. Samples: FFPE serial sections of human lung cancer. Antibody: Affinity purified rabbit anti-WARS (Product # A304-274A) (Lot 1, left image) and (Product # A304-275A) (Lot 1, right image) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB.
Product Details
A304-275A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 421 to 471 of Human Tryptophanyl-tRNA Synthetase.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hWRS; IFI 53; IFP 53; IFP53; Interferon-induced protein 53; TrpRS; tryptophan tRNA ligase 1, cytoplasmic; Tryptophan--tRNA ligase, cytoplasmic; Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase, cytoplasmic; WARS protein
Gene Aliases: GAMMA-2; IFI53; IFP53; TrpRS; WARS; WARS1; WRS
UniProt ID: (Human) P23381, (Mouse) P32921
Entrez Gene ID: (Human) 7453, (Mouse) 22375
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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