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Invitrogen
WDR19 Polyclonal Antibody
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Product Details
PA5-100367
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human WDR19(Accession Q8NEZ3), corresponding to amino acid residues G66-T116.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2849880
Product Specific Information
Antibody detects endogenous levels of total WDR19/IFT144.
Target Information
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains six WD repeats, a clathrin heavy-chain repeat, and three transmembrane domains. This gene is conserved from C. elegans to human. It may participate in androgen-regulated signaling mechanisms or in the vesicular trafficking of androgen-regulated secretory processes. Alternatively spliced transcript variants encoding distinct isoforms have been reported but the full-length nature of one of these variants has not been defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Intraflagellar transport 144 homolog; WD repeat membrane protein PWDMP; WD repeat-containing protein 19
Gene Aliases: ATD5; C330027H04Rik; CED4; D330023L08Rik; DYF-2; DYF2; IFT144; KIAA1638; mKIAA1638; NPHP13; ORF26; Oseg6; PWDMP; RGD1306997; SRTD5; WDR19
UniProt ID: (Human) Q8NEZ3, (Mouse) Q3UGF1
Entrez Gene ID: (Human) 57728, (Rat) 305349, (Mouse) 213081
cell morphogenesis
in utero embryonic development
smoothened signaling pathway
gonad development
embryonic limb morphogenesis
embryonic camera-type eye development
intraciliary retrograde transport
cilium assembly
ear morphogenesis
embryonic cranial skeleton morphogenesis
neurological system process
digestive system development
cilium morphogenesis
ciliary receptor clustering involved in smoothened signaling pathway
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
myotome development
cell projection organization
protein localization to cilium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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