Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody recognizes the full length WDR33 protein.
Immunogen sequence: GRREESFRR GAPPRHEGRA PPRGRDGFPG PEDFGPEENF DASEEAARGR DLRGRGRGTP RGGRKGLLPT PDEFPRFEGG RKPDSWDGNR EPGPGHEHFR DTPRPDHPPH DGHSPASRER SSSLQGMDMA SLPPRKRPWH DGPGTSEHRE MEAPGGPSED RGGKGRGGPG PAQRVPKSGR SSSLDGEHHD GYHRDEPFGG PPGSGTPSRG GRSGSNWGRG SNMNSGPPRR GASRGGGRGR (11098-1336 aa encoded by BC010283)
WDR33 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is highly expressed in testis and the protein is localized to the nucleus. This gene may play important roles in the mechanisms of cytodifferentiation and/or DNA recombination. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ11294; pre-mRNA 3' end processing protein WDR33; WD repeat-containing protein 33; WD repeat-containing protein of 146 kDa; WD repeat-containing protein WDC146
Gene Aliases: NET14; WDC146; WDR33
UniProt ID: (Human) Q9C0J8
Entrez Gene ID: (Human) 55339
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