Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
WDR4 Recombinant Rabbit Monoclonal Antibody (5R7B6)
FIGURE: 1 / 3
WDR4 Antibody (MA5-37987) in IHC (P)
Immunohistochemistry analysis of WDR4 in paraffin-embedded human colon carcinoma. Samples were incubated with WDR4 Monoclonal antibody (Product # MA5-37987) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
MA5-37987
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
5R7B6
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human WDR4 (P57081)
Conjugate
Form
Liquid
Concentration
0.88 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897905
Product Specific Information
Positive Samples: HeLa, HepG2, A-549, Mouse lung, Mouse spleen, Mouse kidney, Rat kidney
Immunogen sequence: AFWCQENCVA LLCDGTPVVY IFQLDARRQQ LVYRQQLAFQ HQVWDVAFEE TQGLWVLQDC QEAPLVLYRP VGDQWQSVPE STVLKKVSGV LRGNWAMLEG S
Target Information
Required for 7-methylguanosine modification of tRNA. This protein is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD). which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes. including cell cycle progression. signal transduction. apoptosis. and gene regulation. This protein is excluded as a candidate for a form of nonsyndromic deafness (DFNB10). but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternative splicing of this gene generates at least 3 transcript variants. two of which diverge at the 3' UTR and thus encode the same protein products.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hWH; mWH; Protein Wuho homolog; TRM82 tRNA methyltransferase 82 homolog; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat-containing protein 4; WD40 repeat protein 4; WDR4
Gene Aliases: AI415180; AI448349; D530049K22Rik; TRM82; TRMT82; WDR4
UniProt ID: (Human) P57081, (Mouse) Q9EP82
Entrez Gene ID: (Human) 10785, (Mouse) 57773, (Rat) 690032
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support