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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • WDR45 Antibodies

          Invitrogen

          WDR45 Polyclonal Antibody

          View all (5) WDR45 antibodies

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          Cite WDR45 Polyclonal Antibody

          • Antibody Testing Data (3)
          WDR45 Antibody in Immunocytochemistry (ICC/IF)
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          WDR45 Antibody in Immunocytochemistry (ICC/IF)
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          FIGURE: 1 / 3

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          WDR45 Antibody (PA5-121118) in ICC/IF

          Immunofluorescence analysis of WDR45 in NIH/3T3 cells. Samples were incubated with WDR45 Polyclonal antibody (Product # PA5-121118) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          WDR45 Antibody in Immunocytochemistry (ICC/IF)
          WDR45 Antibody in Immunocytochemistry (ICC/IF)
          WDR45 Antibody in Western Blot (WB)

          Product Details

          PA5-121118

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 35-148 of human WDR45 (NP_001025067.1).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.42 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2914690

          Product Specific Information

          Positive test controls include: Mouse skeletal muscle, Rat lung.

          Immunogen sequence: EPLMEKGHLD HEQVGSMGLV EMLHRSNLLA LVGGGSSPKF SEISVLIWDD AREGKDSKEK LVLEFTFTKP VLSVRMRHDK IVIVLKNRIY VYSFPDNPRK LFEFDTRDNP KGLC

          Target Information

          This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: WD repeat domain phosphoinositide-interacting protein 4; WD repeat domain X-linked 1; WD repeat domain, X-linked 1; WD repeat-containing protein 45; WIPI-4

          View more View less

          Gene Aliases: C79260; DXImx38e; JM5; Sfc19; Wdr45; Wdrx1; WIPI-4; Wipi4

          View more View less

          UniProt ID: (Rat) Q5U2Y0, (Mouse) Q91VM3

          View more View less

          Entrez Gene ID: (Rat) 302559, (Mouse) 54636

          View more View less

          Function(s)
          phosphatidylinositol-3-phosphate binding phosphatidylinositol-3,5-bisphosphate binding
          Process(es)
          autophagosome assembly mitophagy protein lipidation autophagy cellular response to nitrogen starvation protein localization to pre-autophagosomal structure nucleophagy
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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