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Invitrogen
WDR61 Polyclonal Antibody
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Product Details
PA5-59052
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human WDR61. Recombinant protein control fragment (Product #RP-98085).
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649601
Product Specific Information
Immunogen sequence: DISHTLPIAA SSSLDAHIRL WDLENGKQIK SIDAGPVDAW TLAFSPDSQY LATGTHVGKV NIFGVESGKK EYSLDTR
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
Target Information
SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: meiotic recombination protein REC14; Meiotic recombination REC14 protein homolog; recombination protein REC14; Ski8; SKI8 homolog; Superkiller complex protein 8; WD repeat-containing protein 61
Gene Aliases: 2700038L12Rik; 2810418I05Rik; REC14; RGD1308228; SKI8; SKIC8; WDR61
UniProt ID: (Human) Q9GZS3, (Rat) Q4V7A0, (Mouse) Q9ERF3
Entrez Gene ID: (Human) 80349, (Rat) 363064, (Mouse) 66317
transcription, DNA-templated
Wnt signaling pathway
positive regulation of transcription elongation from RNA polymerase II promoter
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
histone H3-K4 trimethylation
positive regulation of histone H3-K79 methylation
regulation of transcription, DNA-templated
positive regulation of histone methylation
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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