Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
24431-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
WDR7 Fusion Protein Ag19072 (1145-1490 aa encoded by BC131558)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LLTRPRSSS QIPEGFGLTS GGSNYSLARH TCKALTFLLL QPPSPKLPPH STIRRTAIDL IGRGFTVWEP YMDVSAVLMG LLELCADAEK QLANITMGLP LSPAADSARS ARHALSLIAT ARPPAFITTI AKEVHRHTAL AANTQSQQNM HTTTLARAKG EILRVIEILI EKMPTDVVDL LVEVMDIIMY CLEGSLVKKK GLQECFPAIC RFYMVSYYER NHRIAVGARH GSVALYDIRT GKCQTIHGHK GPITAVAFAP DGRYLATYSN TDSHISFWQM NTSLLGSIGM LNSAPQLRCI KTYQVPPVQP ASPGSHNALK LARLIWTSNR NVILMAHDGK EHRFMV (1145-1490 aa encoded by BC131558)
Target Information
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependent exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Rabconnectin-3 beta; rabconnectin-3beta; TGF-beta resistance associated; TGF-beta resistance-associated protein TRAG; WD repeat-containing protein 7
Gene Aliases: AI462727; KIAA0541; mKIAA0541; TRAG; Wd7; WDR7
UniProt ID: (Human) Q9Y4E6, (Mouse) Q920I9, (Rat) Q9ERH3
Entrez Gene ID: (Human) 23335, (Mouse) 104082, (Rat) 66031
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support