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Invitrogen
WDR77 Polyclonal Antibody
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Product Details
PA5-30811
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human WDR77. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548285
Product Specific Information
Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Predicted reactivity: Mouse (87%), Rat (87%), Rhesus Monkey (97%), Chimpanzee (99%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Androgen receptor cofactor p44; MEP-50; Methylosome protein 50; Methylosome protein WDR77; MGC2722; OTTHUMP00000013473; p44/Mep50; RP11-552M11.3; testis tissue sperm-binding protein Li 44a; WD repeat-containing protein 77
Gene Aliases: HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50; WD45; WDR77
UniProt ID: (Human) Q9BQA1
Entrez Gene ID: (Human) 79084
spliceosomal snRNP assembly
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
peptidyl-arginine N-methylation
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
negative regulation of epithelial cell proliferation involved in prostate gland development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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