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Invitrogen
WFDC2 Recombinant Rabbit Monoclonal Antibody (404)
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WFDC2 Antibody (MA5-29645) in IHC (P)
Immunohistochemical staining of human WFDC2 in human ovarian cancer (from 7 donors) with WFDC2 Recombinant Rabbit Monoclonal Antibody (404) (Product # MA5-29645, 1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to the malignant cell.
Product Details
MA5-29645
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
404
Immunogen
Recombinant Human WFDC2/HE4 protein (Met1-Phe124)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785472
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human WFDC2/HE4.
Target Information
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymal protein 4; Epididymal secretory protein E4; epididymis-specific, whey-acidic protein type, four-disulfide core; Major epididymis-specific protein E4; MGC57529; Putative protease inhibitor WAP5; WAP domain containing protein HE4-V4; WAP four-disulfide core domain protein 2
Gene Aliases: dJ461P17.6; EDDM4; HE4; WAP5; WFDC2
UniProt ID: (Human) Q14508
Entrez Gene ID: (Human) 10406
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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