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Invitrogen
WNT10B Monoclonal Antibody (5A7)
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Product Details
MA5-15557
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5A7
Immunogen
Purified recombinant fragment of human WNT10B expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10982343
Product Specific Information
MA5-15557 targets WNT10B in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15557 immunogen is purified recombinant fragment of human WNT10B expressed in E. Coli.
MA5-15557 detects WNT10B which has a predicted molecular weight of approximately 43kDa.
Target Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein Wnt-10b; Protein Wnt-12; wingless-type MMTV integration site family member 10B; wingless-type MMTV integration site family, member 10B; WNT-10B protein
Gene Aliases: SHFM6; WNT-12; WNT10B; WNT12
UniProt ID: (Human) O00744
Entrez Gene ID: (Human) 7480
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
chondrocyte differentiation
lipid metabolic process
cell cycle arrest
smoothened signaling pathway
positive regulation of cell proliferation
positive regulation of G2/M transition of mitotic cell cycle
myoblast differentiation involved in skeletal muscle regeneration
Wnt signaling pathway
neuron differentiation
positive regulation of bone mineralization
positive regulation of epithelial cell differentiation
regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of apoptotic process
cell fate commitment
negative regulation of fat cell differentiation
positive regulation of osteoblast differentiation
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
regulation of skeletal muscle tissue development
skeletal muscle fiber development
negative regulation of epithelial cell proliferation
protein stabilization
sensory perception of taste
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of anagen
canonical Wnt signaling pathway
bone trabecula formation
fungiform papilla development
cellular response to retinoic acid
cellular response to cAMP
cellular response to parathyroid hormone stimulus
hematopoietic stem cell proliferation
cellular response to hydrostatic pressure
positive regulation of canonical Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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