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Invitrogen
WNT2 Polyclonal Antibody
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Product Details
PA5-119628
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within human WNT2 aa 209-263
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2913201
Product Specific Information
Positive Control: PC-3M, mouse brain tissue, Jurkat, human lung tissue.
Subcellular Location: Secreted.
Target Information
WNT2 is a ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Int-1-like protein 1; INT-1-related protein; INT1L 1; IRP; IRP protein; Protein Wnt-2; secreted growth factor; wingless-related MMTV integration site 2; wingless-type MMTV integration site family member 2; WNT 2
Gene Aliases: 2610510E18Rik; INT1L1; IRP; Mirp; Wnt-2; WNT2; Wnt2a
UniProt ID: (Human) P09544, (Mouse) P21552
Entrez Gene ID: (Human) 7472, (Mouse) 22413
positive regulation of endothelial cell proliferation
positive regulation of mesenchymal cell proliferation
lens development in camera-type eye
cell-cell signaling
positive regulation of cell proliferation
Wnt signaling pathway
neurogenesis
neuron differentiation
lung development
cell proliferation in midbrain
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
positive regulation of fibroblast proliferation
positive regulation of neurogenesis
positive regulation of sequence-specific DNA binding transcription factor activity
atrial cardiac muscle tissue morphogenesis
positive regulation of cardiac muscle cell proliferation
canonical Wnt signaling pathway
cardiac epithelial to mesenchymal transition
lung induction
positive regulation of epithelial cell proliferation involved in lung morphogenesis
labyrinthine layer blood vessel development
iris morphogenesis
mammary gland epithelium development
cellular response to retinoic acid
cellular response to transforming growth factor beta stimulus
positive regulation of canonical Wnt signaling pathway
midbrain dopaminergic neuron differentiation
canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
multicellular organism development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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